Effect of cholecystokinin octapeptide on diacylglycerol-PKC signaling pathway in rat pulmonary interstitial macrophages stimulated by lipopolysaccharide1
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منابع مشابه
Effect of cholecystokinin octapeptide on food intake in pigs.
Considerable interest has been aroused by the suggestion that the gut hormone cholecystokinin (CCK) is released during feeding and then acts as a satiety signal (Gibbs et al. 1973). Many studies, in species ranging from the mouse to man, have shown that peripheral administration of CCK, or its octapeptide, will reduce food intake. However, inhibition of feeding could be produced via a satiety s...
متن کاملEffect of octapeptide of cholecystokinin on canine pyloric pressure.
ISENBERG, JON I., AND ATTILA CSENDES. Efect of octapeptide of cholecystokinin on canine pyloric pressure. Am. J. Physiol. 222(2) : 42843 1. 1972.-Intraluminal pressure was measured in five dogs with gastric and duodenal cannulas. Open-tipped perfused tubes were used as pressure sensors. To localize the pylorus (i.e., gastroduodenal junction), transluminal potential difference was recorded. The ...
متن کاملCholecystokinin octapeptide immunization: effect on growth of barrows and gilts.
A study was conducted to validate the previously reported growth response to cholecystokinin octapeptide (CCK-8) immunization in barrows and was extended to include gilts. Group-penned barrows and gilts were used to represent conditions in the swine industry. Thirty-two animals, 19 barrows and 13 gilts, were randomly assigned by sex to four pens and two treatments. The control groups were immun...
متن کاملEffect of Neutrophils on Nitric Oxide Production from Stimulated Macrophages
Background: During the initial phase of an infection, there is an upregulation of inducible nitric oxide synthase in the macrophages for the production of nitric oxide. This is followed by the recruitment of polymorphonuclear leukocytes (neutrophils) which release arginase. Arginase competes with inducible nitric oxide synthase for a common substrate L-arginine. Objective: To investigate whethe...
متن کاملMultiple sources of 1,2-diacylglycerol in isolated rat pancreatic acini stimulated by cholecystokinin. Involvement of phosphatidylinositol bisphosphate and phosphatidylcholine hydrolysis.
Changes in the cellular content of 1,2-diacylglycerol (DAG) in isolated rat pancreatic acini in response to agonist stimulation were studied using a sensitive mass assay. When acini were stimulated by 10 nM COOH-terminal cholecystokinin-octapeptide (CCK8), the increase in DAG was biphasic, consisting of an early peak at 5 s and a second, larger, gradual increase that was maximal by 15 min. The ...
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ژورنال
عنوان ژورنال: Acta Pharmacologica Sinica
سال: 2005
ISSN: 1671-4083,1745-7254
DOI: 10.1111/j.1745-7254.2005.00217.x